Association of British Clinical Diabetologists

Endobarrier Registry

 
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Above - an endobarrier - click for more information

 

Above: a picture of an endobarrier in position - click for more information

 
Above: Endobarrier in overweight patients with diabetes leads to considerable weight loss and improvement in glycaemic control. Click the above slide to see the presentation at EASD 2011 that it was taken from. Click here to see endobarrier publications
 

Above: Before and after Endobarrier - a slide presented at the ADA in 2016 from a presentation suggesting that Endobarrier is likely to reduce cardiovascular events and save lives – click to enlarge and show this patients data. Click here to see the ADA 2016 presentation

Endobarrier Worldwide Registry

Endobarrier is a 60cm tube-like liner made from a thin, flexible and durable impermeable polymer. It is inserted by an endoscopy and prevents food that passes through it from contacting the first two feet of small bowel intestine. In clinical trials it leads to weight loss and improved glycaemic control and may become a useful treatment option in the future.

ABCD and Endobarrier
ABCD is currently funding the REVISE-Diabesity and End-OSA Endobarrier studies, which are supported by the NHS, as National Institute for Health Research’ (NIHR) Clinical (Diabetes) Research Network Portfolio Studies. One year data from the REVISE study was presented at the ADA 2016 as well as at the EASD in 2016, and there has been a BBC news item sparked by this data. There was also a BBC news item following the launch of the End-OSA study of Endobarrier in diabetes with obstructive sleep apnoea.

Need for a registry
Over 3000 patients in the world have had Endobarrier treatment. Those of us who have used it have found that most patients gain considerable improvement in terms of reduction in weight, improvement in diabetes control, reduction in the need for other diabetes medications, in particular insulin, improvement in patient wellbeing and examples from the experience in Birmingham, UK, are shown here. Side effects, such as they are, seem to be acceptable considering the benefit. If the information about all these patients could be collected into a single worldwide registry we would have enormous power to demonstrate the benefits of Endobarrier in relation to the risks. Using the technology already established for the ABCD nationwide and worldwide audits, ABCD has created an independent online tool to collect this data.

Local analysis
The tool facilitates Centres entering data to analyse their own data very easily for the purposes of presentation and publication, etc.

National registries
The German national registry data was presented at the EASD in 2016. We introduce here the independent worldwide Endobarrier registry tool which now allows other nations to easily follow suit and analyse their own national data for the purposes of presentation and publication, etc: The tool very easily allows all the Centres in a Country to combine their data.

Worldwide registry
The tool easily then allows worldwide analysis of all the data in the world and it allows for comparison between countries

Paper forms
If you would like to collect data on paper forms that exactly match the on-line tool then you can download for printing the first visit form and the follow up visit form

Ownership of the data
As well established for the other ABCD national and worldwide audits of new diabetes therapies, the data is jointly owned by all those contributing to the registry and all contributors will be mentioned in all publications utilising the worldwide data. On the safety side the tool will allow us to know the exact frequency of adverse events and the circumstances in which they occur

Registration
All Endobarrier using Centres are therefore encourage to register and enter the data from their Endobarrier treated patients. Data can be added retrospectively or prospectively. Click here to register and join the registry

 Register for the  Endobarrier worldwide Registry

Access the Endobarrier registry on-line tool

Download first visit data entry form that matches the on-line tool

Download follow up visit data entry form that matches the on-line tool

Further information- contact us

Main ABCD homepage

     

Working to support high quality diabetes care in the UK