Association of British Clinical Diabetologists

Empagliflozin Nationwide Audit

 
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Above - empagliflozin significantly reduced death from cardiovascular causes in the EMPA-REG OUTCOME study - click to see the results from that study

 

Above: the EMPA-REG OUTCOME study showed empaglfliflozin conferred impressive renal protection - click to see the renal results

 

Above - the EMP-REG OUTCOME study triggered a new era with regard to diabetes medications with cardiovascular protection, the subject of some editorials in ABCD's journal, the British Journal of Diabetes. Click here to see one of these editorials

 
 

ABCD nationwide empagliflozin audit on N3

About the ABCD nationwide empagliflozin audit

With the launch of the empaagliflozin audit, ABCD is now auditing all three from new class of drugs for diabetes, the SGLT2 inhibitors. As with the ABCD GLP1-receptor agonist audits (exenatide, liraglutide and exenatide QW) it may be that patients being treated with the SGLT2 inhibitors in real clinical practice will be different from those in clinical trials and outcomes may also be different both in terms of safety and efficacy. As with the exenatide QW, dapagliflozin and canagliflozin audits, this audit is again being hosted on N3 - the latest version of NHSnet. Access the on-line tool for the audit does require the user to be on N3 ie in an NHS hospital, GP surgery etc. The audit has a number of objectives.

Web-based audit tool on N3
The audit tool for the empagliflozin audit is very similar to that being used for the dapagliflozin and canagliflozin audits. This will make comparison between the data in the three audits and combining data for analysis of class an easy task. The tool is easy to use. Being on N3 it has optimum security for patient identifiable data with regard to your own patients, but anonymises the data when it is utilised in the national audit. There are some special features with regard to the data export both for your own local analysis and for the nationwide analysis. The export now allows you to choose which data to download for analysis as well as providing all data. It also allows you to choose to download the data aggregated to 2 monthly, 3 monthly, 4 monthly or 6 monthly time points.  The tool has the facility to detect data from the same patient entered in two sites (eg hospital and primary care) and to merge the data when exported - see centres and sites below. As with the canagliflozin audit, to improve patient safety, Boehringer Ingelheim's pharmacovigilance team will be alerted automatically of any serious adverse events. This is in addition to the usual advice that adverse events occurring in the UK should be reported to the yellow card scheme: www.mhra.gov.uk/yellowcard.

Structure of the audit centres and sites
For this audit the concept of centres and sites is utilised in the same way as in the exenatide QW, dapagliflozin and canagliflozin audits. Typically a centre might be an NHS Trust. Sites might be hospitals associated with that Trust, and/or health centres or GP surgeries in the local vicinity. If set up in this structure, designated leaders of the local audit would be given access to download the anonymised data of all the patients associated with the centre for more powerful local analysis of data involving higher numbers. Findings so made through such local analysis could be put forward for further testing on the full national dataset.

Collect data on-line or via paper forms
The on-line audit tool is so easy to use that live data entry in clinic is a real option to be considered. Otherwise to facilitate data collection during clinics there are two paper forms which exactly match the data that can be entered into the audit tool. You can download and print these forms locally or order pre-printed data entry forms.

To download the forms to printout for use, use the following links:

Download first visit data entry form
Download follow up visit data entry form

Non ABCD members
Non ABCD members are welcome to take part in the audit and will be given access to the on-line audit tool when they
register for the audit.

Register to take part in the audit and access to the on-line tool
To register for the audit and be given access to the on-line tool on the ABCD website on N3 click here.

Further information
Further enquiries may be made to the ABCD nationwide audits database administrator of the project, Melissa Cull
   Register for the empagliflozin audit: UK

Register simultaneously for ALL 3 SGLT2 audits: canagliflozin, dapagliflozin and empagliflozin

Access the on-line tool
(UK: you need to be on N3)

Empagliflozin audit objectives

Order preprinted data entry forms

Download first visit data entry form

Download follow up visit data entry form

Further information- contact us

Main ABCD homepage

     

The ABCD nationwide empagliflozin audit is an independent audit supported by an unrestricted grant from Boehringer Ingelheim

Working to support high quality diabetes care in the UK